SCHEMBL1417537

SCHEMBL1417537

Cc1ccc(S(=O)(=O)Nc2ccc(N)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.71
CA2 P00918 2/20 0.71
CA9 Q16790 2/20 0.71
HTT P42858 1/20 0.71
KMT2A Q03164 4/20 0.68
KEAP1 Q14145 1/20 0.68
CA12 O43570 1/20 0.68
ALDH1A1 P00352 5/20 0.68
MAPT P10636 4/20 0.68
MEN1 O00255 3/20 0.68
CYP1A2 P05177 1/20 0.68
CYP3A4 P08684 1/20 0.68
CYP2C19 P33261 1/20 0.68
GAA P10253 1/20 0.65
LMNA P02545 1/20 0.65
MAPK1 P28482 1/20 0.65
GFER P55789 1/20 0.65
MCL1 Q07820 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
ALOX12 P18054 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2240008 1.00 CA1 (0.71) CA1CA2CA9HTTKMT2A
SCHEMBL28754776 0.95 KMT2A (0.73) CA1CA2CA9HTTKMT2A
SCHEMBL10622720 0.91 ALDH1A1 (0.68) CA1CA2CA9HTTKMT2A
SCHEMBL2005010 0.90 CA12 (0.81) CA1CA2CA9HTTKMT2A
SCHEMBL11793140 0.90 CA1 (0.85) CA1CA2CA9HTTKMT2A
SCHEMBL540915 0.90 CA1 (0.85) CA1CA2CA9HTTKMT2A
Phenol SCHEMBL28153349 0.88 KMT2A (0.67) CA1CA2CA9HTTKMT2A
SCHEMBL7141853 0.85 MAPT (0.68) HTTKMT2AALDH1A1MAPTMEN1
SCHEMBL7565259 0.85 CA1 (0.73) CA1CA2CA9HTTKMT2A
SCHEMBL7834044 0.85 HTR6 (0.72) CA1CA2CA9HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798167-A Preparation method of plant growth regulator and application of plant growth regulator in agriculture 贵州工业职业技术学院 2025-04-11 CN claimed
US-20050059657-A1 Aminoisoxazole derivatives active as kinase inhibitors PFIZER ITALIA S.R.L. (IT) 2005-03-17 US claimed
CN-1549714-A Aminoisoxazole derivatives active as kinase inhibitors 2004-11-24 CN claimed
EP-1435948-A1 AMINOISOXAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS Pharmacia Italia S.p.A. (IT) 2004-07-14 EP claimed
WO-2003013517-A1 AMINOISOXAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS PHARMACIA ITALIA S.P.A. (IT) 2003-02-20 WO claimed
EP-0309284-A2 Stabilized carbon black loaded polyolefins UNIROYAL CHEMICAL COMPANY, Inc. (US) 1989-03-29 EP claimed
EP-4676926-A1 BICYCLIC HETEROARYL COMPOUNDS FOR USE AS GPR35 MODULATORS ThirtyFiveBio Limited (GB) 2026-01-14 EP disclosed
CN-119798167-A Preparation method of plant growth regulator and application of plant growth regulator in agriculture 贵州工业职业技术学院 2025-04-11 CN disclosed
WO-2024184650-A1 BICYCLIC HETEROARYL COMPOUNDS FOR USE AS GPR35 MODULATORS. ThirtyFiveBio Limited (GB) 2024-09-12 WO disclosed
CN-117510460-A Benzo [ b ] thiophene derivative containing sulfonamide unit, and preparation method and application thereof 贵州大学 2024-02-06 CN disclosed
CN-117186049-A 2, 2-dimethyl-2H chromene derivative containing sulfonamide unit, and preparation method and application thereof 贵州大学 2023-12-08 CN disclosed
US-20200129458-A1 COMPOUND HAVING ENHANCING ACTIVITY FOR GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIONS AJINOMOTO CO., INC. (JP) 2020-04-30 US disclosed
US-20200129458-A1 COMPOUND HAVING ENHANCING ACTIVITY FOR GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIONS AJINOMOTO CO., INC. (JP) 2020-04-30 US disclosed
WO-2003032986-A1 2' -METHYL-5-(1,3,4-OXADIAZOL-2-YL)-1,1'-BIPHENYL-4-CARBOXAMIDE DERIVATIVES AND THEIR USE AS P38 KINASE INHIBITORS GLAXO GROUP LIMITED (GB) 2003-04-24 WO disclosed
WO-2003032916-A2 ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES STRUCTURAL BIOINFORMATICS INC. (US) 2003-04-24 WO disclosed
WO-2003013517-A1 AMINOISOXAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS PHARMACIA ITALIA S.P.A. (IT) 2003-02-20 WO disclosed
EP-1277729-A1 PPAR (GAMMA) MODULATORS Sankyo Company, Limited (JP) 2003-01-22 EP disclosed
US-4124579-A FOR POLYMERIC MATERIALS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-11-07 US disclosed
US-3979378-A Water-soluble azo dyes having a substituted 2-hydroxypyridone (6) coupling component BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-09-07 US disclosed
US-3957860-A SULFAMIC ACID CIBA-GEIGY AG (CH) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050059657-A1 Aminoisoxazole derivatives active as kinase inhibitors MAP3K9, MAP3K19, MAP4K2 CA1 2406/4885CA2 2764/4885CA9 3355/4885
US-20200129458-A1 COMPOUND HAVING ENHANCING ACTIVITY FOR GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIONS GLP1R, GPR119, GIPR CA1 3303/4885CA2 2248/4885CA9 3130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.