Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 5/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4862162 | 0.84 | HRH1 (0.49) | HRH1HTR1AHDAC6DRD2 | |
| SCHEMBL11359103 | 0.83 | HRH1 (0.58) | HRH1HTR1AHDAC6DRD2 | |
| SCHEMBL12938774 | 0.78 | SRD5A1 (0.45) | HRH1HTR1AARHDAC6 | |
| SCHEMBL27629337 | 0.77 | HRH1 (0.59) | HRH1HTR1AHDAC6DRD2 | |
| SCHEMBL27649837 | 0.77 | HRH1 (0.59) | HRH1HTR1AHDAC6DRD2 | |
| SCHEMBL12194153 | 0.77 | AR (0.46) | HRH1HTR1AARDRD2GAA | |
| SCHEMBL14197432 | 0.76 | HRH1 (0.48) | HRH1HDAC6DRD2 | |
| SCHEMBL4872282 | 0.76 | HRH1 (0.48) | HRH1HDAC6DRD2 | |
| SCHEMBL11350931 | 0.74 | HRH1 (0.48) | HRH1HTR1AARHDAC6DRD2 | |
| SCHEMBL21913053 | 0.74 | HRH1 (0.48) | HRH1HTR1AARHDAC6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351839-B2 | Process for the preparation of 1,2,3,4,8,9,10, 10a-octahydro-7bH-cyclopenta[b][1,4]diazepino-[6,7,1-hi]indole derivatives | WYETH (US) | 2008-04-01 | — | — | US | disclosed |