Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16867367 | 0.74 | KDM1A (0.39) | KDM1A | |
| SCHEMBL19814601 | 0.73 | ALOX15 (0.43) | — | |
| SCHEMBL29669136 | 0.73 | HTR2A (0.43) | — | |
| SCHEMBL8518646 | 0.73 | CYP3A4 (0.43) | KDM1A | |
| SCHEMBL646392 | 0.73 | HTR2A (0.43) | — | |
| SCHEMBL24582723 | 0.71 | TAAR1 (0.37) | — | |
| SCHEMBL2336569 | 0.71 | HDAC4 (0.43) | — | |
| SCHEMBL1604324 | 0.71 | HDAC4 (0.43) | KDM1A | |
| SCHEMBL30344393 | 0.71 | HDAC4 (0.43) | — | |
| SCHEMBL30344664 | 0.71 | HDAC4 (0.43) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060391-A2 | 2- [L-PHENYL-5-HYDR0XY-4ALPHA-METHYL-HEXAHYDR0CYCL0PENTA[F] INDAZ0L-5-YL] ETHYL PHENYL DERIVATIVES AS GLUCOCORTICOID RECEPTOR LIGANDS | MERCK & CO., INC. (US) | 2008-05-22 | — | — | WO | disclosed |