Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 11/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3862095 | 0.85 | LCK (0.37) | LCKS1PR3 | |
| SCHEMBL19829825 | 0.77 | BRD4 (0.40) | LCKTRPA1S1PR3 | |
| SCHEMBL29353882 | 0.72 | LCK (0.45) | LCK | |
| SCHEMBL21384103 | 0.72 | LCK (0.45) | LCK | |
| SCHEMBL30499449 | 0.71 | LCK (0.48) | LCK | |
| SCHEMBL31321350 | 0.71 | LCK (0.48) | LCK | |
| SCHEMBL18211757 | 0.69 | BRD4 (0.39) | LCKTRPA1S1PR3 | |
| SCHEMBL12675269 | 0.68 | BRD4 (0.34) | LCK | |
| SCHEMBL8941838 | 0.67 | BTK (0.47) | LCK | |
| SCHEMBL21872980 | 0.66 | JAK2 (0.41) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064255-A2 | COMPOUNDS MODULATING C-FMS AND/OR C-KIT ACTIVITY AND USES THEREFOR | PLEXXIKON, INC. (US) | 2008-05-29 | — | — | WO | disclosed |