⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372847 | 0.76 | — | — | |
| SCHEMBL15858574 | 0.76 | — | — | |
| SCHEMBL1911605 | 0.74 | — | — | |
| SCHEMBL2175079 | 0.74 | ALDH1A1 (0.48) | — | |
| SCHEMBL17504106 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL10987975 | 0.73 | ALDH1A1 (0.47) | — | |
| SCHEMBL10830269 | 0.72 | HRH1 (0.33) | — | |
| SCHEMBL27995931 | 0.70 | HTT (0.77) | — | |
| SCHEMBL18123078 | 0.69 | — | — | |
| SCHEMBL19370147 | 0.68 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064255-A2 | COMPOUNDS MODULATING C-FMS AND/OR C-KIT ACTIVITY AND USES THEREFOR | PLEXXIKON, INC. (US) | 2008-05-29 | — | — | WO | disclosed |