SCHEMBL14197898

SCHEMBL14197898

c1ccc2oc(-c3cc(-c4cc5ccccc5o4)c4ccc5c(-c6cc7ccccc7o6)cc(-c6cc7ccccc7o6)c6ccc3c4c65)cc2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.58
MAOA P21397 3/20 0.58
KMT2A Q03164 5/20 0.51
MEN1 O00255 3/20 0.51
TDP1 Q9NUW8 2/20 0.51
POLB P06746 1/20 0.48
CTDSP1 Q9GZU7 1/20 0.48
PDE4D Q08499 1/20 0.47
ALOX5 P09917 1/20 0.46
RAB9A P51151 3/20 0.45
PTPRC P08575 1/20 0.45
PTPN1 P18031 1/20 0.45
NPC1 O15118 2/20 0.45
MAPT P10636 1/20 0.45
ADRA2A P08913 2/20 0.44
METAP2 P50579 1/20 0.44
HTR2C P28335 1/20 0.43
GRM4 Q14833 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13953716 0.92 KMT2A (0.54) MAOBMAOAKMT2AMEN1TDP1
SCHEMBL13229080 0.92 KMT2A (0.54) MAOBMAOAKMT2AMEN1TDP1
SCHEMBL19497661 0.92 KMT2A (0.54) MAOBMAOAKMT2AMEN1TDP1
SCHEMBL13229147 0.89 MAOB (0.51) MAOBMAOAKMT2AMEN1TDP1
SCHEMBL13229093 0.89 MAOB (0.51) MAOBMAOAKMT2AMEN1TDP1
SCHEMBL13229108 0.89 MAOB (0.47) MAOBMAOAKMT2AMEN1TDP1
SCHEMBL13229144 0.89 KMT2A (0.51) MAOBMAOAKMT2AMEN1TDP1
SCHEMBL13229095 0.89 KMT2A (0.51) MAOBMAOAKMT2AMEN1TDP1
SCHEMBL13229024 0.88 KMT2A (0.52) MAOBMAOAKMT2AMEN1TDP1
SCHEMBL13229135 0.87 MAOB (0.50) MAOBMAOAKMT2AMEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11177450-B2 Organoelectroluminescent element, and light emission device, display device, and illumination device in which said organoelectroluminescent element is used UDC IRELAND LIMITED (IE) 2021-11-16 US disclosed
US-20140225085-A1 Organoelectroluminescent Element, and Light Emission Device, Display Device, and Illumination Device in which Said Organoelectroluminescent Element is Used UDC IRELAND LIMITED (IE) 2014-08-14 US disclosed
US-20140225085-A1 Organoelectroluminescent Element, and Light Emission Device, Display Device, and Illumination Device in which Said Organoelectroluminescent Element is Used UDC IRELAND LIMITED (IE) 2014-08-14 US disclosed
US-20080105865-A1 Pyrene Based Compound and Light Emitting Transistor Element Using the Same PIONEER CORPORATION (JP) 2008-05-08 US disclosed
EP-1816114-A1 PYRENE COMPOUND AND LIGHT EMITTING TRANSISTOR DEVICE UTILIZING THE SAME Rohm Co., Ltd. (JP) 2007-08-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080105865-A1 Pyrene Based Compound and Light Emitting Transistor Element Using the Same CYP1A1, SULT1A1, SULT1E1 MAOB 2614/4885MAOA 2819/4885KMT2A 2208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.