SCHEMBL14199020

SCHEMBL14199020

Cc1cn(CC(=O)Nc2ccc(-n3ccccc3=O)cc2F)nc1NC(=O)c1ccc(Cl)s1

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13342039 0.85 F10 (1.00) F10
SCHEMBL8266112 0.84 F10 (1.00) F10
SCHEMBL8265102 0.81 F10 (1.00) F10
SCHEMBL8266217 0.80 F10 (0.70) F10
SCHEMBL8265282 0.76 F10 (1.00) F10
SCHEMBL8250903 0.76 F10 (1.00) F10
SCHEMBL8259652 0.76 F10 (0.86) F10
SCHEMBL8257888 0.75 F10 (0.75) F10
SCHEMBL8252767 0.75 F10 (1.00) F10
SCHEMBL8257332 0.75 F10 (1.00) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1846381-B1 HETEROARYLACETAMIDES AS FACTOR Xa INHIBITORS HOFFMANN LA ROCHE (CH) 2008-05-28 EP disclosed