SCHEMBL14199068

SCHEMBL14199068

C=C(C)C(=O)Oc1ccc(NC(=O)C(Br)(Br)Br)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.49
KMT2A Q03164 5/20 0.49
MEN1 O00255 2/20 0.49
ATM Q13315 1/20 0.46
NPSR1 Q6W5P4 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.40
HSD17B10 Q99714 2/20 0.40
PDK1 Q15118 1/20 0.40
PDK2 Q15119 1/20 0.40
PDK3 Q15120 1/20 0.40
PDK4 Q16654 1/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
EPHX2 P34913 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
GAA P10253 2/20 0.38
OPRK1 P41145 1/20 0.38
GPR174 Q9BXC1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2032682 0.83 KMT2A (0.70) ELANEKMT2AMEN1NPSR1L3MBTL1
SCHEMBL9883772 0.82 ELANE (0.44) ELANEKMT2AMEN1ATMNPSR1
SCHEMBL12863515 0.82 RXFP1 (0.56) ELANEKMT2AMEN1ATMNPSR1
SCHEMBL22258850 0.80 MAPT (0.58) ELANEKMT2AMEN1ATMNPSR1
SCHEMBL14622043 0.79 ELANE (0.42) ELANEKMT2AMEN1ATMNPSR1
SCHEMBL14622023 0.79 ELANE (0.42) ELANEKMT2AMEN1ATMNPSR1
SCHEMBL56436 0.79 ELANE (0.69) ELANEKMT2AMEN1ATMSMN1; SMN2
SCHEMBL8834653 0.79 LIPE (0.48) ELANEKMT2AMEN1ATMNPSR1
SCHEMBL22082354 0.78 RXFP1 (0.51) ELANEKMT2AMEN1ATMNPSR1
SCHEMBL17084529 0.78 RXFP1 (0.51) ELANEKMT2AMEN1ATMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080090175-A1 Positive working light sensitive planographic printing plate material and planographic printing plate manufacturing process employing the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-04-17 US disclosed
US-20080090175-A1 Positive working light sensitive planographic printing plate material and planographic printing plate manufacturing process employing the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-04-17 US disclosed
US-7202019-B2 Photothermographic imaging material KONICA MINOLTA HOLDINGS, INC. (JP) 2007-04-10 US disclosed
US-7202019-B2 Photothermographic imaging material KONICA MINOLTA HOLDINGS, INC. (JP) 2007-04-10 US disclosed