Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 10/20 | 0.51 |
| ▸ | FDPS | P14324 | 4/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP14 | P50281 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12060623 | 0.92 | GGPS1 (0.56) | GGPS1FDPSMMP8MMP14MMP1 | |
| SCHEMBL14199561 | 0.85 | GGPS1 (0.44) | GGPS1FDPS | |
| SCHEMBL14199553 | 0.81 | GGPS1 (0.75) | GGPS1FDPS | |
| SCHEMBL14199570 | 0.77 | GGPS1 (0.55) | GGPS1FDPS | |
| SCHEMBL12060618 | 0.75 | GGPS1 (0.44) | GGPS1FDPSMMP2CA9CA14 | |
| SCHEMBL12060532 | 0.75 | GGPS1 (0.70) | GGPS1FDPS | |
| SCHEMBL14199575 | 0.74 | GGPS1 (0.68) | GGPS1FDPS | |
| SCHEMBL14199574 | 0.74 | GGPS1 (0.54) | GGPS1FDPS | |
| SCHEMBL12048206 | 0.73 | GGPS1 (0.52) | GGPS1FDPS | |
| SCHEMBL12060543 | 0.72 | GGPS1 (0.56) | GGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358361-B2 | Biophosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-04-15 | — | — | US | disclosed |