Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 12/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.38 |
| ▸ | CHRNA10 | Q9GZZ6 | 4/20 | 0.38 |
| ▸ | CHRNA9 | Q9UGM1 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12060532 | 0.95 | GGPS1 (0.70) | GGPS1LMNAFDPSHTTRAB9A | |
| SCHEMBL14199553 | 0.93 | GGPS1 (0.75) | GGPS1LMNAFDPSHTTRAB9A | |
| SCHEMBL12060601 | 0.86 | GGPS1 (0.83) | GGPS1LMNAFDPS | |
| SCHEMBL14199574 | 0.77 | GGPS1 (0.54) | GGPS1FDPS | |
| SCHEMBL14199576 | 0.77 | GGPS1 (0.68) | GGPS1FDPS | |
| SCHEMBL14199572 | 0.76 | GGPS1 (0.53) | GGPS1FDPS | |
| SCHEMBL14199567 | 0.76 | GGPS1 (0.61) | GGPS1FDPS | |
| SCHEMBL14199578 | 0.76 | GGPS1 (0.53) | GGPS1FDPS | |
| SCHEMBL14199559 | 0.75 | GGPS1 (0.52) | GGPS1FDPS | |
| SCHEMBL14199562 | 0.74 | GGPS1 (0.51) | GGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358361-B2 | Biophosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-04-15 | — | — | US | disclosed |