Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 17/20 | 0.83 |
| ▸ | FDPS | P14324 | 2/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14199589 | 0.95 | GGPS1 (0.74) | GGPS1FDPS | |
| SCHEMBL12257805 | 0.95 | GGPS1 (0.88) | GGPS1FDPSNR1H4DHODH | |
| SCHEMBL14199576 | 0.90 | GGPS1 (0.68) | GGPS1FDPS | |
| SCHEMBL14199566 | 0.90 | GGPS1 (0.68) | GGPS1FDPS | |
| SCHEMBL12060544 | 0.89 | GGPS1 (0.79) | GGPS1FDPS | |
| SCHEMBL14199567 | 0.86 | GGPS1 (0.61) | GGPS1FDPS | |
| SCHEMBL12060536 | 0.85 | GGPS1 (0.72) | GGPS1FDPS | |
| SCHEMBL12060535 | 0.85 | GGPS1 (0.72) | GGPS1FDPS | |
| SCHEMBL12436806 | 0.80 | GGPS1 (0.65) | GGPS1FDPS | |
| SCHEMBL14199553 | 0.78 | GGPS1 (0.75) | GGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358361-B2 | Biophosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-04-15 | — | — | US | disclosed |