Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 15/20 | 0.68 |
| ▸ | FDPS | P14324 | 2/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12060536 | 0.94 | GGPS1 (0.72) | GGPS1FDPSRXRARXRBGAA | |
| SCHEMBL14199589 | 0.91 | GGPS1 (0.74) | GGPS1FDPSGAAKDM4E | |
| SCHEMBL14199565 | 0.90 | GGPS1 (0.83) | GGPS1FDPS | |
| SCHEMBL14199567 | 0.89 | GGPS1 (0.61) | GGPS1FDPSFFAR1 | |
| SCHEMBL12257838 | 0.87 | GGPS1 (0.66) | GGPS1FDPS | |
| SCHEMBL12060544 | 0.85 | GGPS1 (0.79) | GGPS1FDPSGAAKDM4E | |
| SCHEMBL12257805 | 0.84 | GGPS1 (0.88) | GGPS1FDPS | |
| SCHEMBL12436806 | 0.82 | GGPS1 (0.65) | GGPS1FDPS | |
| SCHEMBL14199553 | 0.81 | GGPS1 (0.75) | GGPS1FDPS | |
| SCHEMBL12257803 | 0.81 | GGPS1 (0.74) | GGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358361-B2 | Biophosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-04-15 | — | — | US | disclosed |