Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 15/20 | 0.80 |
| ▸ | FDPS | P14324 | 2/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14199586 | 1.00 | GGPS1 (0.80) | GGPS1FDPSENPP2S1PR1S1PR3 | |
| SCHEMBL14199569 | 0.96 | GGPS1 (0.74) | GGPS1FDPSENPP2 | |
| SCHEMBL12257807 | 0.94 | GGPS1 (0.86) | GGPS1FDPSENPP2S1PR1S1PR3 | |
| SCHEMBL12060539 | 0.94 | GGPS1 (0.86) | GGPS1FDPSENPP2S1PR1S1PR3 | |
| SCHEMBL12060529 | 0.94 | GGPS1 (0.86) | GGPS1FDPSENPP2S1PR1S1PR3 | |
| SCHEMBL12060626 | 0.91 | GGPS1 (0.77) | GGPS1FDPSENPP2 | |
| SCHEMBL12257842 | 0.84 | GGPS1 (0.57) | GGPS1FDPS | |
| SCHEMBL12257802 | 0.83 | GGPS1 (0.69) | GGPS1FDPS | |
| SCHEMBL14199580 | 0.82 | GGPS1 (0.56) | GGPS1FDPS | |
| SCHEMBL14199572 | 0.80 | GGPS1 (0.53) | GGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358361-B2 | Biophosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2008-04-15 | — | — | US | disclosed |