SCHEMBL14199725

SCHEMBL14199725

CC(P)OCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
IDO1 P14902 1/20 0.44
SLC1A3 P43003 2/20 0.43
SLC1A2 P43004 2/20 0.43
SLC1A1 P43005 2/20 0.43
MEN1 O00255 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
KMT2A Q03164 1/20 0.43
AGXT P21549 1/20 0.43
MAPT P10636 2/20 0.42
ALDH1A1 P00352 2/20 0.42
RCE1 Q9Y256 1/20 0.41
AOC3 Q16853 1/20 0.41
SLC6A2 P23975 3/20 0.41
TAAR1 Q96RJ0 2/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15003 0.81 TSHR (0.52) TSHRIDO1SLC1A3SLC1A2SLC1A1
SCHEMBL1571975 0.81 TSHR (0.52) TSHRIDO1SLC1A3SLC1A2SLC1A1
Ammonia Solution, Strong SCHEMBL21518155 0.79 TSHR (0.50) TSHRIDO1SLC1A3SLC1A2SLC1A1
Lithium SCHEMBL9504699 0.79 TSHR (0.50) TSHRIDO1SLC1A3SLC1A2SLC1A1
SCHEMBL9504704 0.79 TSHR (0.50) TSHRIDO1SLC1A3SLC1A2SLC1A1
SCHEMBL10782592 0.78 TSHR (0.44) TSHRIDO1SLC1A3SLC1A2SLC1A1
SCHEMBL6032737 0.78 TSHR (0.40) TSHRIDO1SLC1A3SLC1A2SLC1A1
SCHEMBL23998026 0.77 TSHR (0.48) TSHRIDO1SLC1A3SLC1A2SLC1A1
SCHEMBL2554445 0.77 TAAR1 (0.52) TSHRIDO1SLC1A3SLC1A2SLC1A1
SCHEMBL5812823 0.77 TSHR (0.48) TSHRIDO1SLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1518673-B1 Photosensitive composition and planographic printing plate precursor FUJIFILM CORP (JP) 2008-05-21 EP disclosed