Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15003 | 0.98 | TSHR (0.52) | TSHRIDO1SLC6A2SLC6A4SLC6A3 | |
| Ammonia Solution, Strong SCHEMBL21518155 | 0.95 | TSHR (0.50) | TSHRIDO1SLC6A2SLC6A4SLC6A3 | |
| Lithium SCHEMBL9504699 | 0.95 | TSHR (0.50) | TSHRIDO1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21465397 | 0.89 | TSHR (0.44) | TSHRIDO1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL649272 | 0.85 | IDO1 (0.44) | IDO1SLC6A2SLC6A4SLC6A3AGXT | |
| SCHEMBL12936629 | 0.85 | IDO1 (0.55) | TSHRIDO1AGXTCYP1A2CYP2D6 | |
| SCHEMBL1571975 | 0.83 | TSHR (0.52) | TSHRIDO1SLC6A2SLC6A4SLC6A3 | |
| Benzoic Acid SCHEMBL4532566 | 0.82 | NR4A2 (0.54) | TSHRSLC6A2SLC6A3SLC1A3SLC1A2 | |
| SCHEMBL19129544 | 0.81 | LTA4H (0.52) | TSHR | |
| SCHEMBL646907 | 0.81 | IDO1 (0.42) | IDO1SLC6A2SLC6A4SLC6A3AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279463-B1 | GRAFT POLYMERIZATION OF SUBSTITUTED STYRENE POLYMERS HAVING PENDANT VINYLIDENE GROUPS | Nippon Paint Co., Ltd. (JP) | 1993-05-26 | — | — | EP | disclosed |
| US-4853436-A | Graft polymerization of substituted styrene polymers having pendant vinylidene groups | NIPPON PAINT CO., LTD. (JP) | 1989-08-01 | — | — | US | disclosed |
| EP-0279463-A2 | Graft polymerization of substituted styrene polymers having pendant vinylidene groups | Nippon Paint Co., Ltd. (JP) | 1988-08-24 | — | — | EP | disclosed |