Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14201277 | 0.84 | PTGER4 (0.54) | PTGER4ALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL14200298 | 0.81 | PTGER4 (0.48) | PTGER4ALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL3534869 | 0.80 | PTGER4 (0.68) | PTGER4ALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL3538284 | 0.70 | PTGER4 (1.00) | PTGER4 | |
| SCHEMBL3537638 | 0.69 | PTGER4 (0.84) | PTGER4 | |
| SCHEMBL3535902 | 0.67 | PTGER4 (0.87) | PTGER4ALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL4690777 | 0.67 | PTGER4 (0.51) | PTGER4ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL13452001 | 0.64 | MAOB (0.37) | ALDH1A1POLBHPGDGAARAB9A | |
| SCHEMBL13354637 | 0.63 | PTGER4 (0.57) | PTGER4ALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL3534956 | 0.63 | PTGER4 (0.69) | PTGER4ALDH1A1MAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603893-B1 | EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LTD (GB) | 2008-05-21 | — | — | EP | disclosed |