Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4691006 | 0.87 | PTGER4 (0.64) | PTGER4LMNAMAOBKDM4EALDH1A1 | |
| SCHEMBL3534869 | 0.86 | PTGER4 (0.68) | PTGER4LMNAMAOBKDM4EALDH1A1 | |
| SCHEMBL4688546 | 0.82 | PTGER4 (0.50) | PTGER4LMNAMAOBKDM4EALDH1A1 | |
| SCHEMBL4691616 | 0.82 | PTGER4 (0.72) | PTGER4MAPTSMN1; SMN2 | |
| SCHEMBL4691034 | 0.78 | PTGER4 (0.51) | PTGER4LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL4690870 | 0.78 | MAOB (0.52) | PTGER4LMNAMAOBAKR1C3AKR1C2 | |
| SCHEMBL4691618 | 0.75 | PTGER4 (0.55) | PTGER4LMNAALDH1A1MAPTNPC1 | |
| SCHEMBL3535902 | 0.74 | PTGER4 (0.87) | PTGER4KDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL3534753 | 0.71 | PTGER4 (0.63) | PTGER4LMNAMAOBKDM4EALDH1A1 | |
| SCHEMBL4688386 | 0.71 | LMNA (0.57) | PTGER4LMNAMAOBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603893-B1 | EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LTD (GB) | 2008-05-21 | — | — | EP | claimed |