Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14200289 | 0.88 | HCAR2 (0.30) | — | |
| SCHEMBL14200283 | 0.84 | — | — | |
| SCHEMBL13633145 | 0.83 | ALDH1A1 (0.37) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL14229674 | 0.81 | CA12 (0.39) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL14200244 | 0.80 | ALDH1A1 (0.34) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL14200277 | 0.78 | ALDH1A1 (0.33) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL14201256 | 0.78 | CA12 (0.36) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL14200293 | 0.77 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL14201257 | 0.76 | CA12 (0.40) | ALDH1A1 | |
| SCHEMBL14200270 | 0.74 | CA12 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |