Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 10/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3535003 | 0.86 | MAPT (0.56) | MAPTKDM4EALDH1A1TSHRHPGD | |
| SCHEMBL14568367 | 0.84 | PTGER4 (0.56) | MAPTKDM4EALDH1A1TSHRHPGD | |
| SCHEMBL14539474 | 0.81 | MAPT (0.51) | MAPTKDM4EALDH1A1TSHRHPGD | |
| SCHEMBL14199639 | 0.78 | MAPT (0.67) | MAPTKDM4EALDH1A1TSHRHPGD | |
| SCHEMBL3534513 | 0.76 | MAPT (0.64) | MAPTKDM4EALDH1A1TSHRHPGD | |
| SCHEMBL3537345 | 0.74 | PTGER4 (0.79) | MAPTKDM4EALDH1A1TSHRHPGD | |
| SCHEMBL12992410 | 0.74 | MAPT (0.61) | MAPTKDM4EALDH1A1TSHRHPGD | |
| SCHEMBL3536337 | 0.72 | MAPT (0.59) | MAPTKDM4EALDH1A1TSHRHPGD | |
| SCHEMBL12991931 | 0.72 | PTGER4 (0.42) | MAPTKDM4EALDH1A1TSHRHPGD | |
| SCHEMBL26467532 | 0.72 | BACE1 (0.35) | MAPTKDM4EALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603893-B1 | EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LTD (GB) | 2008-05-21 | — | — | EP | disclosed |