Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.40 |
| ▸ | KDM6B | O15054 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2953120 | 0.88 | HTR6 (0.63) | HTR6HTR1AKDM4CKDM6B | |
| Hydrochloric Acid SCHEMBL27690417 | 0.87 | HTR6 (0.61) | HTR6HTR1AKDM4CKDM6B | |
| SCHEMBL2965157 | 0.85 | HTR6 (0.53) | HTR6KDM4C | |
| Hydrochloric Acid SCHEMBL2954644 | 0.85 | HTR6 (0.53) | HTR6KDM4C | |
| SCHEMBL2956933 | 0.84 | HTR6 (0.66) | HTR6KDM4C | |
| SCHEMBL2960579 | 0.84 | HTR6 (0.60) | HTR6 | |
| SCHEMBL2959922 | 0.83 | HTR6 (0.49) | HTR6HTR1AKDM4C | |
| Hydrochloric Acid SCHEMBL2965127 | 0.83 | HTR6 (0.59) | HTR6 | |
| SCHEMBL2963199 | 0.82 | HTR6 (0.55) | HTR6 | |
| SCHEMBL2950348 | 0.81 | HTR6 (0.56) | HTR6HTR1AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831191-B1 | CHROMAN DERIVATIVES AND THEIR USE AS 5-HT RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2008-05-21 | — | — | EP | disclosed |