Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.69 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydropiperine SCHEMBL29392462 | 0.81 | TRPV1 (1.00) | TRPV1ALDH1A1HDAC1HDAC3HDAC2 | |
| Tetrahydropiperine SCHEMBL4898699 | 0.81 | TRPV1 (1.00) | TRPV1ALDH1A1HDAC1HDAC3HDAC2 | |
| SCHEMBL14200777 | 0.81 | TRPV1 (0.97) | TRPV1ALDH1A1HDAC1HDAC3HDAC2 | |
| SCHEMBL11261146 | 0.80 | DPP7 (0.65) | TRPV1MAOBALDH1A1HPGDDPP7 | |
| SCHEMBL11698547 | 0.79 | DPP7 (0.67) | TRPV1MAOBALDH1A1HPGDDPP7 | |
| SCHEMBL4953724 | 0.76 | TRPV1 (0.71) | TRPV1ALDH1A1HPGDHDAC1HDAC3 | |
| SCHEMBL7996805 | 0.75 | HRH1 (0.53) | TRPV1ALDH1A1HPGDDPP7MAPT | |
| SCHEMBL19783665 | 0.75 | HDAC1 (0.72) | TRPV1ALDH1A1HDAC1HDAC3HDAC2 | |
| SCHEMBL5191016 | 0.75 | HDAC1 (0.72) | TRPV1ALDH1A1HDAC1HDAC3HDAC2 | |
| SCHEMBL30989338 | 0.75 | HDAC1 (0.72) | TRPV1ALDH1A1HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361685-B2 | Compounds for use in the treatment of skin conditions | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2008-04-22 | — | — | US | disclosed |
| US-7361685-B2 | Compounds for use in the treatment of skin conditions | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2008-04-22 | — | — | US | disclosed |