Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14200742 | 0.95 | KCNH2 (0.32) | KCNH2 | |
| SCHEMBL14200662 | 0.92 | ACACB (0.30) | — | |
| SCHEMBL14200706 | 0.91 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL14200712 | 0.90 | CRHR1 (0.30) | — | |
| SCHEMBL14200646 | 0.89 | KCNH2 (0.31) | KCNH2 | |
| SCHEMBL14200642 | 0.88 | — | — | |
| SCHEMBL14228953 | 0.88 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL14200648 | 0.86 | CRHR1 (0.31) | — | |
| SCHEMBL14200738 | 0.85 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL14200664 | 0.85 | KCNH2 (0.32) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |