Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 17/20 | 0.84 |
| ▸ | CNR1 | P21554 | 14/20 | 0.84 |
| ▸ | TP53 | P04637 | 1/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.84 |
| ▸ | HPGD | P15428 | 1/20 | 0.84 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.84 |
| ▸ | TSHR | P16473 | 1/20 | 0.84 |
| ▸ | MTOR | P42345 | 1/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.84 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.84 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL430254 | 0.91 | CNR2 (1.00) | CNR2CNR1TP53CYP3A4HPGD | |
| SCHEMBL29426317 | 0.91 | CNR2 (1.00) | CNR2CNR1TP53CYP3A4HPGD | |
| SCHEMBL29448220 | 0.91 | CNR2 (1.00) | CNR2CNR1TP53CYP3A4HPGD | |
| SCHEMBL29835924 | 0.91 | CNR2 (1.00) | CNR2CNR1TP53CYP3A4HPGD | |
| SCHEMBL15995037 | 0.87 | CNR2 (0.74) | CNR2CNR1TP53CYP3A4HPGD | |
| SCHEMBL15995039 | 0.85 | CNR2 (0.72) | CNR2CNR1TP53CYP3A4HPGD | |
| SCHEMBL9089051 | 0.84 | CNR2 (0.87) | CNR2CNR1TP53CYP3A4HPGD | |
| SCHEMBL8932661 | 0.83 | CNR2 (1.00) | CNR2CNR1TP53CYP3A4HPGD | |
| SCHEMBL10068292 | 0.82 | CNR2 (0.85) | CNR2CNR1TP53CYP3A4HPGD | |
| SCHEMBL5801098 | 0.82 | CNR1 (0.73) | CNR2CNR1TP53CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358245-B2 | Treatment of gastroesophageal reflux disease | ASTRAZENCA AB (SE) | 2008-04-15 | — | — | US | disclosed |