SCHEMBL5801098

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6753402	0.92	CNR1 (0.83)	CNR1CNR2LMNACYP1A2CYP2D6
	SCHEMBL3240118	0.89	HIF1A (0.72)	CNR1CNR2LMNACYP1A2CYP2D6
	SCHEMBL6024947	0.86	PTGS1 (0.66)	CNR1CNR2LMNACYP1A2CYP2D6
	SCHEMBL8932661	0.83	CNR2 (1.00)	CNR1CNR2CYP1A2CYP2C9TSHR
	SCHEMBL5797719	0.82	HIF1A (0.80)	CNR1CNR2LMNACYP1A2CYP2D6
	SCHEMBL18500885	0.82	AKR1C3 (0.79)	CNR2LMNACYP1A2CYP2D6CYP2C9
	SCHEMBL29386464	0.82	HIF1A (0.80)	CNR1CNR2LMNACYP1A2CYP2D6
	SCHEMBL3240332	0.82	AKR1C3 (0.75)	CNR1CNR2LMNACYP1A2CYP2D6
	SCHEMBL29454968	0.82	AKR1C3 (0.75)	CNR1CNR2LMNACYP1A2CYP2D6
	Indomethacin SCHEMBL28072579	0.82	PTGS2 (0.98)	CNR2LMNACYP1A2CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.