Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14200390 | 0.90 | TP53 (0.32) | CA2 | |
| SCHEMBL14200424 | 0.86 | — | — | |
| SCHEMBL14200208 | 0.84 | CA1 (0.43) | CA1CA12CA14CA2CA7 | |
| SCHEMBL14200183 | 0.83 | CA1 (0.39) | CA1CA12CA14CA2CA7 | |
| SCHEMBL14200413 | 0.83 | PIK3CD (0.36) | — | |
| SCHEMBL14200184 | 0.82 | CA1 (0.48) | CA1CA12CA14CA2CA7 | |
| SCHEMBL14201305 | 0.81 | CA1 (0.40) | CA1CA12CA14CA2CA7 | |
| SCHEMBL14229375 | 0.81 | CA1 (0.40) | CA1CA12CA14CA2 | |
| SCHEMBL14200353 | 0.79 | CA1 (0.39) | CA1CA12CA14CA2CA7 | |
| SCHEMBL14200430 | 0.79 | CNR2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |