Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649740 | 0.89 | ALDH1A1 (0.50) | ALDH1A1HTTKDM4EMAPTGAA | |
| Water SCHEMBL4695201 | 0.88 | ALDH1A1 (0.49) | ALDH1A1HTTKDM4EMAPTGAA | |
| SCHEMBL4651312 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HTTKDM4EMAPTGAA | |
| SCHEMBL8688689 | 0.81 | ALDH1A1 (0.71) | ALDH1A1HTTKDM4EMAPTGAA | |
| SCHEMBL4650518 | 0.79 | KMT2A (0.50) | ALDH1A1HTTKDM4EMAPTGAA | |
| SCHEMBL4650280 | 0.79 | KMT2A (0.50) | ALDH1A1HTTKDM4EMAPTGAA | |
| SCHEMBL4650513 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HTTKDM4EMAPTGAA | |
| SCHEMBL8688620 | 0.78 | ALDH1A1 (0.67) | ALDH1A1HTTKDM4EMAPTGAA | |
| SCHEMBL4650312 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HTTKDM4EMAPTGAA | |
| SCHEMBL4651062 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HTTKDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008051244-A2 | ANTHRANILIC ACID DERIVATIVES USEFUL IN TREATING INFECTION WITH HEPATITIS C VIRUS | WYETH (US) | 2008-05-02 | — | — | WO | disclosed |