Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | PDE8B | O95263 | 1/20 | 0.47 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.45 |
| ▸ | AHCY | P23526 | 4/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NEK2 | P51955 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7104678 | 0.83 | ADORA2A (0.52) | ADORA2AADORA1ADORA2BPDE8B | |
| SCHEMBL21504439 | 0.78 | PDE8B (0.52) | ADORA2AADORA1ADORA2BADORA3PDE8B | |
| SCHEMBL21759036 | 0.77 | PDE8B (0.46) | ADORA2AADORA1ADORA2BADORA3PDE8B | |
| SCHEMBL13851102 | 0.77 | ADORA2A (0.53) | ADORA2AADORA1ADORA2BADORA3PDE8B | |
| SCHEMBL14201624 | 0.76 | PDE8B (0.44) | ADORA2APDE8B | |
| SCHEMBL8357822 | 0.76 | ADORA2A (0.59) | ADORA2AADORA1ADORA2BPDE8BAHCY | |
| SCHEMBL8357826 | 0.76 | ADORA2A (0.59) | ADORA2AADORA1ADORA2BPDE8BAHCY | |
| SCHEMBL4315191 | 0.76 | PDE8B (0.46) | ADORA2APDE8B | |
| SCHEMBL24236965 | 0.73 | PDE8B (0.48) | ADORA2AADORA1ADORA2BADORA3PDE8B | |
| SCHEMBL1635576 | 0.73 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADCY1AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096903-A1 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-04-24 | — | — | US | disclosed |
| US-20080096903-A1 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096903-A1 | SULFAMOYL-CONTAINING DERIVATIVES AND USES THEREOF | HSP90AB2P, HSP90AB1, HSP90AA1 | ADORA2A 4635/4885ADORA1 4822/4885ADORA2B 4770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.