Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | FGB | P02675 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5022978 | 0.87 | CNR1 (0.49) | ALDH1A1MAPTKDM4EGAAHPGD | |
| SCHEMBL5016478 | 0.87 | CNR1 (0.52) | ALDH1A1MAPTKDM4EGAAHPGD | |
| SCHEMBL6254 | 0.83 | CA12 (0.54) | ALDH1A1MAPTKDM4ETSHRHSD17B10 | |
| SCHEMBL15282372 | 0.83 | TTR (0.47) | ALDH1A1MAPTKDM4EGAAHPGD | |
| SCHEMBL29349851 | 0.83 | CA12 (0.54) | ALDH1A1MAPTKDM4ETSHRHSD17B10 | |
| SCHEMBL18270521 | 0.82 | TTR (0.46) | ALDH1A1MAPTKDM4EGAAHPGD | |
| SCHEMBL3384286 | 0.82 | CA12 (0.53) | ALDH1A1MAPTKDM4ETSHRHSD17B10 | |
| SCHEMBL3384278 | 0.82 | CA12 (0.53) | ALDH1A1MAPTKDM4ETSHRHSD17B10 | |
| SCHEMBL12221061 | 0.82 | TTR (0.46) | ALDH1A1MAPTKDM4EGAAHPGD | |
| Hydrochloric Acid SCHEMBL14833086 | 0.82 | TSHR (0.55) | ALDH1A1MAPTKDM4ETSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365223-B2 | Method for selective targeting of apoptotic cells and small molecule ligands used thereof | NST NEUROSURVIVAL TECHNOLOGIES LTD (IL) | 2008-04-29 | — | — | US | disclosed |
| US-7365223-B2 | Method for selective targeting of apoptotic cells and small molecule ligands used thereof | NST NEUROSURVIVAL TECHNOLOGIES LTD (IL) | 2008-04-29 | — | — | US | disclosed |