Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | RGS12 | O14924 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5016478 | 0.97 | CNR1 (0.52) | CNR1CNR2L3MBTL1MAPTMEN1 | |
| SCHEMBL14228843 | 0.90 | TSHR (0.44) | CNR1CNR2L3MBTL1MAPTMEN1 | |
| SCHEMBL10815702 | 0.88 | CNR1 (0.55) | CNR1CNR2L3MBTL1MAPTMEN1 | |
| SCHEMBL14201709 | 0.87 | ALDH1A1 (0.56) | CNR1CNR2MAPTPOLBHTT | |
| SCHEMBL9626477 | 0.84 | TTR (0.50) | MEN1KMT2ATDP1CYP1A2TSHR | |
| SCHEMBL7514004 | 0.84 | L3MBTL1 (0.58) | CNR1CNR2L3MBTL1USP2POLB | |
| SCHEMBL5015678 | 0.84 | TSHR (0.51) | CNR1CNR2L3MBTL1MAPTMEN1 | |
| SCHEMBL12221061 | 0.84 | TTR (0.46) | MAPTTDP1MAPK1CYP1A2TSHR | |
| SCHEMBL21347987 | 0.83 | CA12 (0.47) | CNR1CNR2L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL12041809 | 0.82 | TTR (0.45) | CNR1CNR2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110319293-A1 | SYNTHETIC PROTEASE SUBSTRATES, ASSAY METHODS USING SUCH SUBSTRATES AND KITS FOR PRACTICING THE ASSAY | LIFESENSORS, INC. | 2011-12-29 | — | — | US | disclosed |
| US-7365223-B2 | Method for selective targeting of apoptotic cells and small molecule ligands used thereof | NST NEUROSURVIVAL TECHNOLOGIES LTD (IL) | 2008-04-29 | — | — | US | disclosed |
| US-20060160901-A1 | Method for selective targeting of apoptotic cells and small molecule ligands used thereof | APOSENSE LTD. (IL) | 2006-07-20 | — | — | US | disclosed |
| EP-1643958-A2 | METHOD FOR SELECTIVE TARGETING OF APOPTOTIC CELLS AND SMALL MOLECULE LIGANDS USED THEREOF | NST Neurosurvival Technologies Ltd. (IL) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004110339-A2 | METHOD FOR SELECTIVE TARGETING OF APOPTOTIC CELLS AND SMALL MOLECULE LIGANDS USED THEREOF | NST NEUROSURVIVAL TECHNOLOGIES LTD. (IL) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160901-A1 | Method for selective targeting of apoptotic cells and small molecule ligands used thereof | BAD, BAX, CASP3 | CNR1 1283/4885CNR2 1168/4885L3MBTL1 1216/4885 |
| US-20110319293-A1 | SYNTHETIC PROTEASE SUBSTRATES, ASSAY METHODS USING SUCH SUBSTRATES AND KITS FOR PRACTICING THE ASSAY | SENP1, STUB1, SENP7 | CNR1 4783/4885CNR2 4880/4885L3MBTL1 709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.