Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731348 | 0.73 | MCL1 (0.47) | RAB9ASTING1NPC1ALDH1A1POLB | |
| SCHEMBL66532 | 0.73 | STING1 (0.36) | RAB9ASTING1NPC1ALDH1A1NPSR1 | |
| SCHEMBL12680721 | 0.69 | STING1 (0.33) | STING1ADRA2ACLCN2GAAALDH1A1 | |
| SCHEMBL714300 | 0.67 | KMT2A (0.40) | RAB9AADRA2ACLCN2NPC1KMT2A | |
| SCHEMBL30313251 | 0.67 | KMT2A (0.40) | RAB9AADRA2ACLCN2NPC1KMT2A | |
| SCHEMBL24904854 | 0.66 | ALDH1A1 (0.38) | RAB9ASTING1NPC1KMT2AGAA | |
| SCHEMBL12680462 | 0.65 | — | — | |
| SCHEMBL22905070 | 0.64 | KDM4E (0.48) | RAB9ASTING1NPC1KMT2AGAA | |
| SCHEMBL29443055 | 0.64 | KDM4E (0.48) | RAB9ASTING1NPC1KMT2AGAA | |
| SCHEMBL4801701 | 0.63 | STING1 (0.50) | RAB9ASTING1ALDH1A1RXFP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057469-A1 | SMALL ORGANIC MOLECULE REGULATORS OF CELL PROLIFERATION | WYETH (US) | 2008-05-15 | — | — | WO | disclosed |