Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 11/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5048284 | 0.78 | SLC29A1 (0.41) | SLC29A1 | |
| SCHEMBL14203634 | 0.77 | CYP1A2 (0.44) | SLC29A1CYP1A2CDK1HTR3EMEN1 | |
| SCHEMBL14203593 | 0.77 | CYP1A2 (0.42) | SLC29A1CYP1A2 | |
| SCHEMBL5040334 | 0.76 | SLC29A1 (0.71) | SLC29A1 | |
| SCHEMBL6666246 | 0.73 | CYP1A2 (0.68) | SLC29A1CYP1A2CDK1MAPT | |
| SCHEMBL6664688 | 0.69 | SLC29A1 (0.57) | SLC29A1CYP1A2 | |
| SCHEMBL5042024 | 0.68 | CYP1A2 (0.54) | SLC29A1CYP1A2ADORA2AADORA1 | |
| SCHEMBL6426384 | 0.64 | CYP1A2 (0.59) | CYP1A2CDK1ADORA2AADORA1 | |
| SCHEMBL14203577 | 0.64 | CYP1A2 (0.42) | SLC29A1CYP1A2 | |
| SCHEMBL6661513 | 0.63 | SLC29A1 (0.49) | SLC29A1CYP1A2CDK1MAPTADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358235-B2 | Analogs of nitrobenzylthioinosine | GRUENENTHAL GMBH (DE) | 2008-04-15 | — | — | US | disclosed |
| US-7358235-B2 | Analogs of nitrobenzylthioinosine | GRUENENTHAL GMBH (DE) | 2008-04-15 | — | — | US | disclosed |