Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 15/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666246 | 0.86 | CYP1A2 (0.68) | SLC29A1CYP1A2HTTPKMHPGD | |
| SCHEMBL6663342 | 0.79 | ADORA1 (0.45) | SLC29A1CYP1A2HTTPKMTSHR | |
| SCHEMBL10746648 | 0.78 | ALDH1A1 (0.43) | SLC29A1CYP1A2HTTPKML3MBTL1 | |
| SCHEMBL14203624 | 0.77 | CYP1A2 (0.46) | SLC29A1CYP1A2 | |
| SCHEMBL14203593 | 0.75 | CYP1A2 (0.42) | SLC29A1CYP1A2TSHR | |
| SCHEMBL14203577 | 0.75 | CYP1A2 (0.42) | SLC29A1CYP1A2 | |
| SCHEMBL14228867 | 0.75 | SLC29A1 (0.71) | SLC29A1CYP1A2 | |
| SCHEMBL5049881 | 0.74 | SLC29A1 (1.00) | SLC29A1 | |
| SCHEMBL14203592 | 0.74 | CYP1A2 (0.40) | SLC29A1CYP1A2 | |
| SCHEMBL6661284 | 0.72 | HTT (0.63) | SLC29A1CYP1A2HTTPKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444982-A1 | The use of purine derivatives as selective kinase inhibitors | MERCKLE GMBH (DE) | 2004-08-11 | — | — | EP | disclosed |