Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.33 |
| ▸ | CD44 | P16070 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23507847 | 0.88 | PNMT (0.30) | PNMT | |
| SCHEMBL24384896 | 0.84 | HTR2C (0.31) | — | |
| SCHEMBL8279313 | 0.83 | PNMT (0.31) | PNMTCD44MAOB | |
| SCHEMBL8239929 | 0.82 | — | — | |
| SCHEMBL24765325 | 0.75 | — | — | |
| SCHEMBL19241137 | 0.72 | — | — | |
| SCHEMBL17968444 | 0.71 | — | — | |
| SCHEMBL6301684 | 0.68 | CRBN (0.36) | — | |
| SCHEMBL17734069 | 0.68 | PNMT (0.32) | PNMTCD44MAOB | |
| SCHEMBL9987289 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260185-B | Deuterated derivative of corydaline and stephanine and preparation method thereof | 杨征 | 2024-09-24 | — | — | CN | disclosed |
| CN-112812112-B | Preparation method of isoquinoline alkaloid L-corydaline | 杨征 | 2024-06-28 | — | — | CN | disclosed |
| WO-2021163629-A1 | INHIBITORS OF ULK1/2 AND METHODS OF USING SAME | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-08-19 | — | — | WO | disclosed |
| EP-3197883-B1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2020-03-18 | — | — | EP | disclosed |
| CN-110156789-A | A kind of synthetic method of azacyclo- and quinazoline compounds | 东华理工大学 | 2019-08-23 | — | — | CN | disclosed |
| EP-2430019-B1 | COMPOUNDS WITH TWO FUSED BICYCLIC HETEROARYL MOIETIES AS MODULATORS OF LEUKOTRIENE A4 HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2013-09-18 | — | — | EP | disclosed |
| WO-2008051637-A2 | PYRIDAZINONE COMPOUNDS | ANADYS PHARMACEUTICALS, INC. (US) | 2008-05-02 | — | — | WO | disclosed |