Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 18/20 | 0.59 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4482910 | 0.92 | KCNA5 (0.59) | KCNA5ABCC9FBP1 | |
| SCHEMBL13865145 | 0.81 | KCNA5 (0.71) | KCNA5 | |
| SCHEMBL2825424 | 0.71 | KCNA5 (0.69) | KCNA5 | |
| SCHEMBL4465077 | 0.71 | ABCB1 (0.52) | KCNA5 | |
| SCHEMBL4478494 | 0.70 | KCNA5 (0.54) | KCNA5 | |
| SCHEMBL4490339 | 0.70 | NPC1 (0.46) | KCNA5 | |
| SCHEMBL4479165 | 0.67 | MEN1 (0.48) | ABCC9 | |
| SCHEMBL4466275 | 0.67 | RAB9A (0.47) | — | |
| SCHEMBL4490240 | 0.67 | KCNA5 (0.57) | KCNA5 | |
| SCHEMBL4484985 | 0.67 | KCNA5 (0.57) | KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368582-B2 | Amidomethyl-substituted 2-(4-sulfonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl compounds, a process and intermediates for their production, and pharmaceutical compositions containing them | SOLVAY PHARMACEUTICALS GMBH (DE) | 2008-05-06 | — | — | US | disclosed |