Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 20/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 10/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 10/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4864731 | 1.00 | ITGAL (0.40) | ITGALITGB2ICAM1 | |
| SCHEMBL4866024 | 1.00 | ITGAL (0.40) | ITGALITGB2ICAM1 | |
| SCHEMBL4848534 | 0.89 | ITGAL (0.46) | ITGALITGB2ICAM1 | |
| SCHEMBL4865762 | 0.83 | ITGAL (0.42) | ITGALITGB2ICAM1 | |
| SCHEMBL14040721 | 0.82 | ITGAL (0.46) | ITGALITGB2ICAM1 | |
| SCHEMBL4797574 | 0.82 | TRPV4 (0.31) | ITGALITGB2ICAM1 | |
| SCHEMBL4801893 | 0.81 | TRPV4 (0.33) | ITGALITGB2ICAM1 | |
| SCHEMBL14040688 | 0.80 | ITGAL (0.44) | ITGALITGB2ICAM1 | |
| SCHEMBL8354466 | 0.80 | ITGAL (0.44) | ITGALITGB2ICAM1 | |
| SCHEMBL4856989 | 0.80 | ITGAL (0.44) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375128-B2 | Inhibitors of α1 β2 integrin mediated cell adhesion | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2008-05-20 | — | — | US | disclosed |