Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732787 | 0.92 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2LMNAPRSS12 | |
| SCHEMBL4784366 | 0.83 | FASN (0.49) | MEN1KMT2ASMN1; SMN2LMNAPRSS12 | |
| SCHEMBL4737601 | 0.82 | FASN (0.59) | MEN1KMT2ASMN1; SMN2LMNANPSR1 | |
| SCHEMBL14210096 | 0.78 | FASN (0.55) | SMN1; SMN2LMNAMAPTNPSR1 | |
| SCHEMBL14209226 | 0.75 | FASN (0.59) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14209842 | 0.75 | KDM4E (0.57) | POLBMAPTNPSR1 | |
| SCHEMBL14210046 | 0.71 | FASN (0.60) | LMNA | |
| SCHEMBL4731259 | 0.70 | SMN1; SMN2 (0.54) | MEN1KMT2ASMN1; SMN2LMNANPSR1 | |
| SCHEMBL14209877 | 0.69 | FASN (0.58) | — | |
| SCHEMBL16799516 | 0.69 | FASN (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |