Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409617 | 0.83 | GPR119 (0.50) | GPR119POLBMAPTALDH1A1LMNA | |
| SCHEMBL14335007 | 0.83 | GPR119 (0.53) | GPR119POLBMAPTALDH1A1LMNA | |
| SCHEMBL12212576 | 0.82 | GPR119 (0.57) | GPR119POLBMAPTJAK2JAK1 | |
| SCHEMBL11361492 | 0.82 | GPR119 (0.57) | GPR119POLBMAPTJAK2JAK1 | |
| SCHEMBL2245357 | 0.82 | GPR119 (0.51) | GPR119POLBMAPTALDH1A1LMNA | |
| SCHEMBL30594366 | 0.82 | GPR119 (0.51) | GPR119POLBMAPTALDH1A1LMNA | |
| SCHEMBL7698320 | 0.81 | GPR119 (0.56) | GPR119POLBMAPTALDH1A1JAK2 | |
| SCHEMBL19268020 | 0.81 | GPR119 (0.51) | GPR119MAPTALDH1A1LMNAMET | |
| SCHEMBL20835982 | 0.81 | GPR119 (0.56) | GPR119POLBMAPTJAK2JAK1 | |
| SCHEMBL2489495 | 0.81 | GPR119 (0.56) | GPR119POLBMAPTLMNAJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297136-A2 | INSECTICIDAL PYRIDYLPIPERIDINE COMPOUNDS | Syngenta Participations AG (CH) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009138219-A2 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-11-19 | — | — | WO | disclosed |