Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | EBP | Q15125 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1420970 | 1.00 | MCHR1 (0.40) | MCHR1CCR3KMT2APROKR1GSK3A | |
| SCHEMBL1463213 | 0.92 | MCHR1 (0.41) | MCHR1CCR3KMT2APROKR1GSK3A | |
| SCHEMBL1462896 | 0.92 | MCHR1 (0.41) | MCHR1CCR3PROKR1GSK3AGSK3B | |
| SCHEMBL1463178 | 0.92 | MCHR1 (0.41) | MCHR1CCR3KMT2APROKR1GSK3A | |
| SCHEMBL1463314 | 0.92 | MCHR1 (0.41) | MCHR1CCR3KMT2APROKR1GSK3A | |
| SCHEMBL1463179 | 0.92 | MCHR1 (0.41) | MCHR1CCR3KMT2APROKR1GSK3A | |
| SCHEMBL1462897 | 0.92 | MCHR1 (0.41) | MCHR1CCR3PROKR1GSK3AGSK3B | |
| SCHEMBL9884602 | 0.91 | MCHR1 (0.40) | MCHR1CCR3PROKR1EBPSIGMAR1 | |
| SCHEMBL1463142 | 0.90 | MCHR1 (0.39) | MCHR1CCR3KMT2APROKR1GSK3A | |
| SCHEMBL1463145 | 0.90 | MCHR1 (0.39) | MCHR1CCR3KMT2APROKR1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193362-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-06-05 | — | — | US | disclosed |
| EP-2297136-B1 | INSECTICIDAL PYRIDYLPIPERIDINE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-28 | — | — | EP | disclosed |
| US-20110071191-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-03-24 | — | — | US | disclosed |
| EP-2297136-A2 | INSECTICIDAL PYRIDYLPIPERIDINE COMPOUNDS | Syngenta Participations AG (CH) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009138219-A2 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071191-A1 | INSECTICIDAL COMPOUNDS | CBR3, CBR1, ACHE | MCHR1 351/4885CCR3 253/4885KMT2A 2609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.