Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.56 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.56 |
| ▸ | ITGAV | P06756 | 1/20 | 0.56 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.56 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
| ▸ | MC4R | P32245 | 10/20 | 0.55 |
| ▸ | MC5R | P33032 | 10/20 | 0.55 |
| ▸ | MC3R | P41968 | 10/20 | 0.55 |
| ▸ | MC1R | Q01726 | 10/20 | 0.55 |
| ▸ | CTSG | P08311 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | GRB7 | Q14451 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | TSLP | Q969D9 | 2/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12353630 | 0.91 | CACNA1B (0.59) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL15188725 | 0.90 | ITGB3 (0.59) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL26200789 | 0.90 | ITGB3 (0.49) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL10033238 | 0.89 | ITGB3 (0.54) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL10033240 | 0.89 | MC4R (0.55) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL13532020 | 0.89 | ITGB3 (0.53) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL12307274 | 0.88 | MC4R (0.55) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL26200764 | 0.88 | ITGB3 (0.49) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL12307752 | 0.87 | MC4R (0.53) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL19605481 | 0.87 | ITGB3 (0.55) | ITGB3ITGB1ITGAVITGA5ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368474-B2 | Radiofluorination methods | GE HEALTHCARE LIMITED (GB) | 2008-05-06 | — | — | US | disclosed |