Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | THRA | P10827 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14211797 | 0.98 | L3MBTL1 (0.43) | ESR1L3MBTL1THRBTHRAMAPT | |
| SCHEMBL16852425 | 0.94 | ESR1 (0.41) | ESR1L3MBTL1THRBTHRAMAPT | |
| SCHEMBL12113646 | 0.94 | ESR1 (0.41) | ESR1L3MBTL1THRBTHRAMAPT | |
| SCHEMBL14211796 | 0.93 | CYP2C19 (0.43) | ESR1L3MBTL1MAPTNR5A1LMNA | |
| SCHEMBL16852417 | 0.92 | L3MBTL1 (0.39) | ESR1L3MBTL1THRBTHRAMAPT | |
| SCHEMBL19160557 | 0.89 | NR5A1 (0.50) | L3MBTL1THRBTHRAMAPTNR5A1 | |
| SCHEMBL19160350 | 0.89 | NR5A1 (0.50) | L3MBTL1THRBTHRAMAPTNR5A1 | |
| SCHEMBL19160763 | 0.89 | NR5A1 (0.50) | L3MBTL1THRBTHRAMAPTNR5A1 | |
| SCHEMBL19160349 | 0.87 | L3MBTL1 (0.46) | ESR1L3MBTL1THRBTHRAMAPT | |
| SCHEMBL19160420 | 0.87 | L3MBTL1 (0.55) | ESR1L3MBTL1THRBTHRAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357637-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-11-09 | — | — | US | disclosed |
| US-9982194-B2 | Liquid-crystalline media | MERECK PATENT GMBH (DE) | 2018-05-29 | — | — | US | disclosed |
| US-20180119010-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-05-03 | — | — | US | disclosed |
| US-20170306232-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-10-26 | — | — | US | disclosed |
| US-9777216-B2 | Liquid crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2017-10-03 | — | — | US | disclosed |
| US-20170044436-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20160208170-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2016-07-21 | — | — | US | disclosed |
| US-9347002-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2016-05-24 | — | — | US | disclosed |
| US-20150203758-A1 | LIQUID-CRYSTALLINE MEDIA | MERCK PATENT GMBH (DE) | 2015-07-23 | — | — | US | disclosed |
| US-20150036095-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-02-05 | — | — | US | disclosed |
| US-20140028964-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-01-30 | — | — | US | disclosed |
| US-20130207038-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2013-08-15 | — | — | US | disclosed |
| US-20130183460-A1 | LIQUID-CRYSTALLINE MEDIA | MERCK PATENT GMBH (DE) | 2013-07-18 | — | — | US | disclosed |
| US-20120305843-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160208170-A1 | LIQUID-CRYSTALLINE MEDIUM | NEFM, VIM, PLG | ESR1 2400/4885L3MBTL1 4366/4885THRB 4351/4885 |
| US-20120305843-A1 | LIQUID CRYSTALLINE MEDIUM | NEFM, VIM, PLG | ESR1 3264/4885L3MBTL1 3925/4885THRB 4430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.