Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 19/20 | 0.91 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14211170 | 0.97 | CNR1 (0.86) | CNR1CYP2C9CYP2C19CYP3A4NR3C1 | |
| SCHEMBL14211173 | 0.96 | CNR1 (0.85) | CNR1CYP2C9CYP2C19CYP3A4NR3C1 | |
| SCHEMBL14212434 | 0.96 | CNR1 (0.85) | CNR1CYP2C9CYP2C19CYP3A4NR3C1 | |
| SCHEMBL14181112 | 0.96 | CNR1 (0.85) | CNR1CYP2C9CYP2C19CYP3A4NR3C1 | |
| SCHEMBL4798385 | 0.95 | CNR1 (1.00) | CNR1CYP2C9CYP2C19CYP3A4NR3C1 | |
| SCHEMBL14212433 | 0.95 | CNR1 (0.84) | CNR1CYP2C9CYP2C19CYP3A4NR3C1 | |
| SCHEMBL14212187 | 0.95 | CNR1 (0.84) | CNR1CYP2C9CYP2C19CYP3A4NR3C1 | |
| SCHEMBL14210241 | 0.94 | CNR1 (0.84) | CNR1CYP2C9CYP2C19CYP3A4NR3C1 | |
| SCHEMBL14181098 | 0.93 | CNR1 (0.80) | CNR1CYP2C9CYP2C19CYP3A4NR3C1 | |
| SCHEMBL14181110 | 0.93 | CNR1 (0.80) | CNR1CYP2C9CYP2C19CYP3A4NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378418-B2 | Azabicyclic heterocycles as cannabinoid receptor modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-27 | — | — | US | disclosed |
| EP-1697370-B1 | AZABICYCLIC HETEROCYCLES AS CANNABINOID RECEPTOR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2007-04-25 | — | — | EP | disclosed |