SCHEMBL14211981

SCHEMBL14211981

c1ccc(-c2ccc(-c3nc4ccc5ccccc5c4nc3-c3ccc(-c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.46
KDM4E B2RXH2 4/20 0.46
LMNA P02545 3/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
MEN1 O00255 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
GAA P10253 2/20 0.46
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
MAPT P10636 1/20 0.45
RECQL P46063 1/20 0.45
DHODH Q02127 4/20 0.44
PRMT5 O14744 1/20 0.44
PRMT3 O60678 1/20 0.44
CARM1 Q86X55 1/20 0.44
EHMT2 Q96KQ7 1/20 0.44
PRMT6 Q96LA8 1/20 0.44
PRMT1 Q99873 1/20 0.44
WDR77 Q9BQA1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15818339 0.96 LMNA (0.47) KMT2AKDM4ELMNAL3MBTL1MEN1
SCHEMBL21282042 0.90 CYP1A1 (0.47) KMT2AKDM4ELMNAL3MBTL1MEN1
SCHEMBL21707337 0.90 KDM4E (0.62) KMT2AKDM4ELMNAL3MBTL1MEN1
SCHEMBL13020033 0.90 TDP1 (0.62) KDM4ELMNAL3MBTL1TDP1GAA
SCHEMBL21941950 0.87 KDM4E (0.54) KMT2AKDM4ELMNAL3MBTL1MEN1
SCHEMBL14211978 0.86 CYP1B1 (0.49) NPC1RAB9ASMN1; SMN2PRMT5PRMT3
SCHEMBL14211976 0.86 TDP1 (0.56) KMT2AKDM4ELMNAL3MBTL1MEN1
SCHEMBL14211979 0.86 KDM4E (0.56) KDM4ELMNAL3MBTL1TDP1GAA
SCHEMBL23759547 0.84 LMNA (0.39) KMT2AKDM4ELMNAL3MBTL1MEN1
SCHEMBL25038073 0.83 NPC1 (0.38) KMT2AKDM4ELMNAL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7355340-B2 Quinoxaline derivatives, organic semiconductor device and electroluminescent device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-04-08 US disclosed
US-7355340-B2 Quinoxaline derivatives, organic semiconductor device and electroluminescent device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-04-08 US disclosed