Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.81 |
| ▸ | ITGAV | P06756 | 17/20 | 0.81 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.81 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 7/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 6/20 | 0.49 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6418885 | 0.91 | ITGB3 (0.78) | ITGB3ITGAVITGA2BITGB6ITGB1 | |
| SCHEMBL6418879 | 0.91 | ITGB3 (0.78) | ITGB3ITGAVITGA2BITGB6ITGB1 | |
| SCHEMBL244675 | 0.90 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB6ITGB1 | |
| SCHEMBL29899937 | 0.90 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB6ITGB1 | |
| SCHEMBL538331 | 0.90 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB6ITGB1 | |
| SCHEMBL29571589 | 0.90 | ITGB3 (1.00) | ITGB3ITGAVITGA2BITGB6ITGB1 | |
| SCHEMBL328724 | 0.89 | ITGB3 (0.77) | ITGB3ITGAVITGA2BITGB6ITGB1 | |
| SCHEMBL6419002 | 0.86 | ITGB3 (0.79) | ITGB3ITGAVITGA2BITGB6ITGB1 | |
| SCHEMBL6418750 | 0.86 | ITGB3 (0.79) | ITGB3ITGAVITGA2BITGB6ITGB1 | |
| SCHEMBL12010936 | 0.85 | ITGB3 (0.76) | ITGB3ITGAVITGA2BITGB6ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368566-B2 | Process and intermediates for preparing benzazepines | SMITHKLINE BEECHAM CORPORATION (US) | 2008-05-06 | — | — | US | disclosed |