SCHEMBL14212992

SCHEMBL14212992

c1ccc(-c2nc(-c3ccccc3)nc(-n3c4ccccc4c4cc5c(cc43)c3ccc4c6ccccc6n(-c6nc(-c7ccccc7)nc(-c7ccccc7)n6)c4c3n5-c3ccccc3)n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.44
KDM4E B2RXH2 1/20 0.44
ATM Q13315 1/20 0.44
KMT2A Q03164 4/20 0.35
IL1R1 P14778 1/20 0.35
ABCG2 Q9UNQ0 3/20 0.35
MEN1 O00255 3/20 0.35
HTT P42858 2/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.34
PTGER4 P35408 1/20 0.34
MAT2A P31153 2/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
RAB9A P51151 1/20 0.33
PRMT5 O14744 1/20 0.33
RXRA P19793 1/20 0.32
GAA P10253 1/20 0.32
MAPK8 P45983 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2754645 0.96 L3MBTL1 (0.46) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL16940907 0.95 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL12690999 0.95 L3MBTL1 (0.45) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL12691507 0.95 L3MBTL1 (0.45) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL16940877 0.95 L3MBTL1 (0.41) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL14213000 0.94 L3MBTL1 (0.46) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL30021164 0.93 L3MBTL1 (0.50) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL30367723 0.93 L3MBTL1 (0.50) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL126253 0.93 L3MBTL1 (0.50) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL17246689 0.93 L3MBTL1 (0.43) L3MBTL1KDM4EATMKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9133205-B2 Organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2015-09-15 US disclosed
US-9133205-B2 Organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2015-09-15 US disclosed
EP-2535958-B1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEM CO (JP) 2014-10-15 EP disclosed
US-20120305904-A1 Organic Electroluminescent Device NIPPON STEEL CHEMICAL CO., LTD. (JP) 2012-12-06 US disclosed
US-20120305904-A1 Organic Electroluminescent Device NIPPON STEEL CHEMICAL CO., LTD. (JP) 2012-12-06 US disclosed