Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL1285922 | 0.99 | CTSB (0.58) | CTSBCYP2C9ALOX15HSD17B10GAA | |
| SCHEMBL4819066 | 0.90 | CTSB (0.60) | CTSBCYP2C9ALOX15HSD17B10GAA | |
| SCHEMBL5717835 | 0.87 | CTSB (0.58) | CTSBCYP2C9ALOX15HSD17B10GAA | |
| SCHEMBL4909115 | 0.84 | CYP2A13 (0.55) | CYP2C9ALOX15HSD17B10POLBCYP3A4 | |
| SCHEMBL20496783 | 0.84 | CNR2 (0.56) | CYP2C9ALOX15HSD17B10POLBCYP3A4 | |
| SCHEMBL20496757 | 0.84 | CYP2A13 (0.55) | CYP2C9ALOX15HSD17B10POLBCYP3A4 | |
| SCHEMBL1421327 | 0.83 | SMN1; SMN2 (0.55) | CTSBCYP2C9ALOX15HSD17B10GAA | |
| Hydrochloric Acid SCHEMBL11621047 | 0.83 | MAPT (0.48) | CTSBCYP2C9ALOX15HSD17B10POLB | |
| Hydrochloric Acid SCHEMBL27831975 | 0.82 | SMN1; SMN2 (0.54) | CTSBCYP2C9ALOX15HSD17B10GAA | |
| SCHEMBL13338345 | 0.81 | CTSB (0.54) | CTSBCYP2C9ALOX15HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1840470-B | Improved process for treating gases containing hydrogen sulphide and sulphur dioxide | INST FRANCAIS DU PETROLE | 2012-05-30 | — | — | CN | claimed |
| EP-1700631-B1 | Improved process for treating gases containing hydrogen sulfur and sulfur dioxide | INST FRANCAIS DU PETROLE (FR) | 2010-06-30 | — | — | EP | claimed |
| US-7597872-B2 | catalytic system, comprising a compound containing at least one functional group A consisting of a carboxylic acid function and at least one functional group B comprising a nitrogen atom and which can produce an acid-base type type reaction with A type functional group, soluble in alcoholic solvent | INSTITUT FRANCAIS DU PETROLE (FR) | 2009-10-06 | — | — | US | claimed |
| CN-1840470-A | Improved process for treating gases containing hydrogen sulfur and sulfur dioxide | INST FRANCAIS DU PETROLE (FR) | 2006-10-04 | — | — | CN | claimed |
| US-20060204433-A1 | Process for treating a gas containing hydrogen sulphide and sulphur dioxide | INSTITUT FRANCAIS DU DETROLE (FR) | 2006-09-14 | — | — | US | claimed |
| EP-2778156-B1 | Phenoxypyridinylamide derivatives and their use in the treatment of PDE4 mediated disease states | ASTRAZENECA AB (SE) | 2016-11-30 | — | — | EP | disclosed |
| EP-2778156-A1 | Phenoxypyridinylamide derivatives and their use in the treatment of PDE4 mediated disease states | AstraZeneca AB (Publ) (SE) | 2014-09-17 | — | — | EP | disclosed |
| CN-102105448-B | Phenoxypyridinylamide derivatives and use thereof in the treatment of PDE4 mediated disease states | ASTRAZENECA AB | 2013-11-13 | — | — | CN | disclosed |
| US-8273774-B2 | Phenoxypyridinylamide compounds | ASTRAZENECA AB (SE) | 2012-09-25 | — | — | US | disclosed |
| CN-1840470-B | Improved process for treating gases containing hydrogen sulphide and sulphur dioxide | INST FRANCAIS DU PETROLE | 2012-05-30 | — | — | CN | disclosed |
| US-7973079-B2 | Methods and compounds for treating retinol-related diseases | REVISION THERAPEUTICS, INC. (US) | 2011-07-05 | — | — | US | disclosed |
| CN-102105448-A | Phenoxypyridinylamide derivatives and their use in the treatment of PDE4 mediated disease states | ASTRAZENECA AB | 2011-06-22 | — | — | CN | disclosed |
| US-6232342-B1 | CATHEPSIN K INHIBITOR FOR TREATING OSTEOPOROSIS, GINGIVITIS, PERIODONTITIS, ARTHRITIS, OSTEOARTHRITIS RHEUMATOID ARTHRITIS, PAGET'S DISEASE, HYPERCALCEMIA OF MALIGNANCY AND METABOLIC BONE DISEASES | SMITHKLINE BEECHAM CORPORATION | 2001-05-15 | — | — | US | disclosed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | disclosed |
| US-6057362-A | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-02 | — | — | US | disclosed |
| US-5998470-A | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1999-12-07 | — | — | US | disclosed |
| EP-0934291-A4 | — | SMITHKLINE BEECHAM CORP (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0934291-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| CN-1207095-A | Protease inhibitors | SMITHKLINE BEECHAM CORP (US) | 1999-02-03 | — | — | CN | disclosed |
| WO-1997016433-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-09 | — | — | WO | disclosed |