Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16744077 | 0.92 | THRB (0.61) | THRBTSHRMAPTBLMTDP1 | |
| SCHEMBL124287 | 0.92 | THRB (0.61) | THRBTSHRMAPTBLMTDP1 | |
| SCHEMBL28001101 | 0.89 | THRB (0.53) | THRBTSHRMAPTBLMTDP1 | |
| SCHEMBL40323 | 0.89 | THRB (0.53) | THRBTSHRMAPTBLMTDP1 | |
| Succinic Acid SCHEMBL28001100 | 0.89 | THRB (0.53) | THRBTSHRMAPTBLMTDP1 | |
| Ethylene SCHEMBL19516917 | 0.87 | THRB (0.52) | THRBTSHRMAPTBLMTDP1 | |
| SCHEMBL10708383 | 0.87 | THRB (0.52) | THRBTSHRMAPTBLMTDP1 | |
| Ethylene SCHEMBL19516611 | 0.87 | THRB (0.52) | THRBTSHRMAPTBLMTDP1 | |
| SCHEMBL28959481 | 0.86 | THRB (0.66) | THRBTSHRMAPTBLMTDP1 | |
| SCHEMBL1478120 | 0.86 | THRB (0.55) | THRBTSHRMAPTBLMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329776-B2 | Dental composition containing a polyfunctional (meth)acrylate comprising urethane, urea or amide groups, method of production and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-12-11 | — | — | US | disclosed |