Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15783291 | 1.00 | TSHR (0.56) | TSHRTHRBTDP1ALDH1A1POLB | |
| SCHEMBL12780621 | 0.89 | TDP1 (0.51) | TSHRTHRBTDP1ALDH1A1POLB | |
| SCHEMBL15783288 | 0.89 | TDP1 (0.51) | TSHRTHRBTDP1ALDH1A1POLB | |
| SCHEMBL169664 | 0.89 | THRB (0.58) | TSHRTHRBTDP1ALDH1A1POLB | |
| SCHEMBL31208489 | 0.88 | THRB (0.50) | TSHRTHRBTDP1ALDH1A1POLB | |
| SCHEMBL29519175 | 0.88 | THRB (0.50) | TSHRTHRBTDP1ALDH1A1POLB | |
| SCHEMBL4569974 | 0.88 | TDP1 (0.50) | TSHRTHRBTDP1ALDH1A1POLB | |
| SCHEMBL16308965 | 0.87 | THRB (0.56) | TSHRTHRBTDP1ALDH1A1POLB | |
| SCHEMBL4644631 | 0.87 | TSHR (0.68) | TSHRTHRBTDP1ALDH1A1POLB | |
| SCHEMBL29519022 | 0.86 | TDP1 (0.51) | TSHRTHRBTDP1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329776-B2 | Dental composition containing a polyfunctional (meth)acrylate comprising urethane, urea or amide groups, method of production and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-12-11 | — | — | US | disclosed |