Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.77 |
| ▸ | DGKA | P23743 | 1/20 | 0.68 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PAM | P19021 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13572554 | 0.98 | TSHR (0.80) | TSHRDGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL13531314 | 0.98 | TSHR (0.80) | TSHRDGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL12768712 | 0.98 | TSHR (0.80) | TSHRDGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL13531296 | 0.98 | TSHR (0.80) | TSHRDGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL20276199 | 0.97 | DGKA (0.72) | TSHRDGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL20276150 | 0.97 | DGKA (0.72) | TSHRDGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL9769723 | 0.97 | DGKA (0.72) | TSHRDGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL20276146 | 0.97 | DGKA (0.72) | TSHRDGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL20276261 | 0.97 | DGKA (0.72) | TSHRDGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL20276157 | 0.97 | DGKA (0.72) | TSHRDGKAPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329776-B2 | Dental composition containing a polyfunctional (meth)acrylate comprising urethane, urea or amide groups, method of production and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-12-11 | — | — | US | disclosed |