Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PGD | P52209 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.34 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.34 |
| ▸ | GRN | P28799 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | THRA | P10827 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19011981 | 0.78 | MAPK1 (0.48) | MAPK1 | |
| SCHEMBL276400 | 0.78 | — | — | |
| SCHEMBL10417537 | 0.75 | MAPK1 (0.48) | MAPK1PGDCACNA2D1CACNB3CACNA1C | |
| SCHEMBL26811369 | 0.75 | MAPK1 (0.48) | MAPK1PGDCACNA2D1CACNB3CACNA1C | |
| SCHEMBL9395777 | 0.75 | SLC22A6 (0.50) | MAPK1PGDGRNSORT1SLC22A6 | |
| SCHEMBL4837493 | 0.75 | SLC22A6 (0.50) | MAPK1PGDGRNSORT1SLC22A6 | |
| SCHEMBL4837485 | 0.75 | SLC22A6 (0.50) | MAPK1PGDGRNSORT1SLC22A6 | |
| SCHEMBL11761433 | 0.75 | CACNA2D1 (0.46) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL804682 | 0.75 | CACNA2D1 (0.46) | CACNA2D1CACNB3CACNA1CPGRADRA1A | |
| SCHEMBL27936231 | 0.75 | CACNA2D1 (0.46) | CACNA2D1CACNB3CACNA1CPGRADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329927-B2 | Water-soluble and water-insoluble, ring opening metathesis polymerization products, monomers and related methods | UNIVERSITY OF MASSACHUSETTS (US) | 2012-12-11 | — | — | US | disclosed |