Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19011834 | 0.85 | MAPK1 (0.41) | MAPK1 | |
| SCHEMBL20102819 | 0.85 | MAPK1 (0.41) | MAPK1 | |
| SCHEMBL12555905 | 0.85 | MAPK1 (0.46) | MAPK1 | |
| SCHEMBL13034048 | 0.84 | MAPK1 (0.55) | MAPK1 | |
| SCHEMBL11927544 | 0.79 | CYP3A4 (0.46) | MAPK1 | |
| SCHEMBL28186037 | 0.78 | CYP3A4 (0.38) | MAPK1 | |
| SCHEMBL14213288 | 0.78 | MAPK1 (0.40) | MAPK1 | |
| SCHEMBL13073321 | 0.76 | MAPK1 (0.42) | MAPK1 | |
| SCHEMBL12285564 | 0.74 | MAPK1 (0.52) | MAPK1 | |
| SCHEMBL17471306 | 0.74 | MAPK1 (0.52) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365563-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2023-11-16 | — | — | US | disclosed |
| US-11168101-B2 | Crystal of cyclic phosphonic acid sodium salt and method for manufacturing same | OTSUKA CHEMICAL CO., LTD. (JP) | 2021-11-09 | — | — | US | disclosed |
| WO-2021127337-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| US-10774100-B2 | Crystal of cyclic phosphonic acid sodium salt and method for manufacturing same | OTSUKA CHECMIAL CO., LTD. (JP) | 2020-09-15 | — | — | US | disclosed |
| US-20200277317-A1 | CRYSTAL OF CYCLIC PHOSPHONIC ACID SODIUM SALT AND METHOD FOR MANUFACTURING SAME | OTSUKA CHEMICAL CO., LTD. (JP) | 2020-09-03 | — | — | US | disclosed |
| EP-3181573-B1 | CRYSTAL OF CYCLIC PHOSPHONIC ACID SODIUM SALT AND METHOD FOR MANUFACTURING SAME | OTSUKA CHEMICAL CO LTD (JP) | 2020-06-17 | — | — | EP | disclosed |
| US-20190330251-A1 | CRYSTAL OF CYCLIC PHOSPHONIC ACID SODIUM SALT AND METHOD FOR MANUFACTURING SAME | OTSUKA CHEMICAL CO., LTD. (JP) | 2019-10-31 | — | — | US | disclosed |
| US-10385081-B2 | Crystal of cyclic phosphonic acid sodium salt and method for manufacturing same | OTSUKA CHEMICAL CO., LTD. (JP) | 2019-08-20 | — | — | US | disclosed |
| US-20180208614-A1 | CRYSTAL OF CYCLIC PHOSPHONIC ACID SODIUM SALT AND METHOD FOR MANUFACTURING SAME | OTSUKA CHEMICAL CO., LTD. (JP) | 2018-07-26 | — | — | US | disclosed |
| EP-3181573-A1 | CRYSTAL OF CYCLIC PHOSPHONIC ACID SODIUM SALT AND METHOD FOR MANUFACTURING SAME | Otsuka Chemical Co., Ltd. (JP) | 2017-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11168101-B2 | Crystal of cyclic phosphonic acid sodium salt and method for manufacturing same | PPM1A, PPP1CA, PPM1G | MAPK1 449/4885 |
| US-10774100-B2 | Crystal of cyclic phosphonic acid sodium salt and method for manufacturing same | PPM1A, PPM1G, PPP1CA | MAPK1 329/4885 |
| US-20180208614-A1 | CRYSTAL OF CYCLIC PHOSPHONIC ACID SODIUM SALT AND METHOD FOR MANUFACTURING SAME | PPM1A, PPP1CA, PPM1G | MAPK1 403/4885 |
| US-20200277317-A1 | CRYSTAL OF CYCLIC PHOSPHONIC ACID SODIUM SALT AND METHOD FOR MANUFACTURING SAME | PPM1A, PPP1CA, PPM1G | MAPK1 449/4885 |
| US-20230365563-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | KRAS, NRAS, BRAF | MAPK1 81/4885 |
| US-20190330251-A1 | CRYSTAL OF CYCLIC PHOSPHONIC ACID SODIUM SALT AND METHOD FOR MANUFACTURING SAME | PPM1A, PPM1G, PPP1CA | MAPK1 329/4885 |
| US-10385081-B2 | Crystal of cyclic phosphonic acid sodium salt and method for manufacturing same | PPM1A, PPP1CA, PPM1G | MAPK1 403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.